RT Journal Article
SR Electronic
A1 Rabišková, Miloslava
A1 Třináctý, Jiří
A1 Sýkora, Tomáš
A1 Doležal, Petr
T1 Post-ruminal delivery systems
JF Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
YR 2015
VO 52
IS 2
SP 143
OP 148
DO 10.11118/actaun200452020143
UL https://acta.mendelu.cz/artkey/acu-200402-0016.php
AB Livestock industry and organization for animal wellfare underlie the need for drug and nutrient delivery systems for ruminants that protect active ingredients from ruminal fermentation. To deliver drugs or nutrients directly to the small intestine for absorption, therapeutical systems must meet the safety and cost criteria. An effective post-ruminal delivery system is a prerequisite to implement some significant advances in animal nutrition and health in ruminants. Comparing with the products developed for human use, cost constraints have impeded the development of effective post-ruminal delivery systems and rumenstable products. This article outlines physiological and technical considerations encountered in the design of effective post-ruminal delivery systems. The requirements and formulation of a pH-dependent rumen stable coating systems and possible future developments will be discussed.