PT  - JOURNAL ARTICLE
AU  - Rabišková, Miloslava
AU  - Třináctý, Jiří
AU  - Sýkora, Tomáš
AU  - Doležal, Petr
TI  - Post-ruminal delivery systems
DP  - 2015 Jul 3
TA  - Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis
PG  - 143--148
VI  - 52
IP  - 2
AID - 10.11118/actaun200452020143
IS  - 12118516
AB  - Livestock industry and organization for animal wellfare underlie the need for drug and nutrient delivery systems for ruminants that protect active ingredients from ruminal fermentation. To deliver drugs or nutrients directly to the small intestine for absorption, therapeutical systems must meet the safety and cost criteria. An effective post-ruminal delivery system is a prerequisite to implement some significant advances in animal nutrition and health in ruminants. Comparing with the products developed for human use, cost constraints have impeded the development of effective post-ruminal delivery systems and rumenstable products. This article outlines physiological and technical considerations encountered in the design of effective post-ruminal delivery systems. The requirements and formulation of a pH-dependent rumen stable coating systems and possible future developments will be discussed.